clinical, epidemiological, laboratory and imaging aspects of brucellosis with and without neurological involvemen
نویسندگان
چکیده
brucellosis is an endemic disease in our country. neurobrucellosis occurs in 5 to 10% of cases, and can present at any stage of of the disease. this study was undertaken to evaluate clinical, epidemiological and paraclinical aspects of brucellosis with and without neurological manifestations. data of 30 patients, 15 cases with nervous system involvement (neurobrucellosis) and 15 cases without neurological complication (brucellosis) were collected and analyzed. constitutional manifestations of the disease were detected with nearly the same frequencies in both groups. exceptions were headache which was more common in patients with neurobrucellosis (73% vs. 33%) and arthralgia which was detected more frequently in cases with brucellosis than neurobrucellosis (53% vs. 13%). signs and symptoms of meningeal irritation and disturbances of consciousness were the most common manifestations in cases with neurobrullosis, which had been detected in 60% and 46.7% of cases, respectively. less common neurological presentations, in decreasing order of frequency were ophthalmoplegia, papilledema and seizures, spastic weakness of limbs, hearing loss and spinal epidural abscess. in two patients with negative serum and csf agglutinin test, diagnosis of neurobrucellosis was made by blood and csf cultures. in patients with neurobrucellosis, mri of brain and spinal cord showed abnormalities in 5/15(33.3%) of cases, including decreased lateral ventricular volume due to brain swelling (2/15), hydrocephalus with periventricular edema and meningeal enhancement in posterior fossa (1/15), multiple hypodense periventricular lesions, ischemic or demyelinating in nature (1/15) and spinal epidural abscess (1/15). brucellosis should be kept in mind in patients with neurological presentations.
منابع مشابه
Clinical, Epidemiological, Laboratory and Imaging Aspects of Brucellosis with and without Neurological Involvement
Brucellosis is an endemic disease in our country. Neurobrucellosis occurs in 5 to 10% of cases, and can present at any stage of of the disease. This study was undertaken to evaluate clinical, epidemiological and paraclinical aspects of brucellosis with and without neurological manifestations. Data of 30 patients, 15 cases with nervous system involvement (neurobrucellosis) and 15 cases without n...
متن کاملepidemiological, clinical, and treatment aspects of brucellosis in khorramabad, iran
background: brucellosis as a zoonosis is still a public health problem in many countries such as iran. to perform preventive, control, and eradication policies about the disease, we need the exact epidemiologic information and patterns of brucellosis in the country. in this study, we investigated the epidemiological, clinical, and treatment aspects of diseases in patients who had a record in sh...
متن کاملEpidemiological and clinical aspects of human brucellosis in Central Greece.
The confirmed cases of human brucellosis in the area of Larissa in Central Greece from 2003 to 2005 were analyzed to assess the features of the affected population and to determine the factors influencing the acquisition of infection. Data of patients infected by Brucella spp. concerning age, gender, occupation, date of diagnosis and the observed symptoms were collected from regional hospitals,...
متن کاملepidemiological features, clinical manifestation and laboratory findings of patients with brucellosis
background brucellosis as a zoonotic infectious disease is endemic in iran and due to the variation in clinical and laboratory findings, its diagnosis is often delayed. objectives the aim of this study was to determine clinical and laboratory aspects of the disease in khuzestan. patients and methods medical records of 81 admitted patients with a diagnosis of brucellosis were reviewed. the study...
متن کاملBrucellosis epidemiological and clinical aspects (Is brucellosis a major public health problem in Bosnia and Herzegovina?).
Brucellosis is primarily an animal disease, and in them it passes as an asymptomatic chronic infection. In humans, brucellosis can be acute, sub-acute and/or chronic disease, but its geographical distribution follows the pattern found in animals. After the last war, the first Brucella cases in Bosnia and Herzegovina were reported in 2000, in returnees, owners of donated livestock. The objective...
متن کاملEpidemiological, clinical and laboratory features of patients hospitalized with 2009 pandemic influenza in north of Iran
Background: The clinical manifestations and outcome of influenza infection differ between various patients in the world. The purpose of this study was to assess the clinical manifestations of patients with confirmed or suspected novel H1N1 flu infection in Sari, North of Iran. Methods: From September 2009 to January 2010, the patients’ data were collected by retrospective chart review of medica...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
acta medica iranicaجلد ۴۵، شماره ۱، صفحات ۶۳-۶۸
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023